Diablo 4's endgame is where the true fun—and the real challenge—begins. If you're aiming to dominate the highest pit tiers, obliterate Uber bosses, and walk the lands of Sanctuary as a mythical powerhouse, you'll need more than just a solid build. From tampering and masterworking gear to farming runes Diablo 4 materials, resources, and eventually crafting mythical uniques, this guide will walk you through everything you need to know to reach your class's max potential.

1. The First Step to Greatness: Reaching Level 60 and Choosing a Build

Before diving into the complexities of the endgame, your journey begins with reaching level 60 and selecting a strong build. With countless guides available online, finding a viable build tailored to your class is easy. But the build is just the foundation—maximizing its potential requires deep investment in gear systems like tampering and masterworking.

2. Tampering: Enabling True Build Synergy

Tampering is the art of refining your gear by adding powerful affixes that can make or break a build. Don't overlook this process; many builds rely heavily on specific affixes to function optimally. Take the Quill Volley Spiritborn build, for example—it requires barrier generation, resource generation, and additional Resolve stacks to truly shine.

Each item allows about five or six tampering rolls per category. If you get an excellent roll on one affix but a poor one on the other, use the Scroll of Restoration to reset your tampering attempts. These scrolls drop frequently, especially in higher-tier pit runs, and allow you to retry the rolls without losing the good affixes already applied.

3. Masterworking: Scaling Your Stats

Once your gear is tempered, the next step is masterworking. This upgrades the stats of your gear across several levels:

    Levels 1–4 are inexpensive and offer 5% boosts to all affixes per level (including tampered ones).

    Levels 5–8 are more costly but offer significant gains.

    Every fourth level (4, 8, 12) provides an additional 25% boost to one random stat.

Masterworking your weapon to 8/8 is critical for most builds, and ideally, you should aim for 4/8 on other legendaries to confidently tackle Torment Tiers 3 and 4.

However, from level 8 onward, costs—especially in Obducite, the key resource—skyrocket. That's why efficient farming methods become essential.

4. Farming Obducite: Top Methods

To keep your gear progression sustainable, you'll need tons of Obducite. Here are the top methods:

Infernal Hordes (6-Wave Runs):

    The quickest and most rewarding method.

    Use Ether to convert into caches of materials.

    At Torment Tier 4, 1 Ether = 320+ Obducite.

Exploit Strategy (Before It's Patched):

    Turn off Pet Auto-Pickup to avoid collecting Ether.

    After defeating the final boss, don't pick up Ether.

    Collect Ether one by one and repeatedly reopen the cache chest—it resets after each Ether pickup.

    Result: Thousands of Obducite in minutes.

Nightmare Dungeons:

    Guaranteed 250–500 Obducite per run.

    Fast clears in 2–3 minutes.

    Events and elite mobs inside dungeons also drop extra resources.

Salvaging Masterworked Items:

    Reclaim large amounts of Obducite.

    Always salvage replaced gear rather than selling.

5. Runes: The Core of Mythical Power

With the arrival of the new expansion, runes have become integral to many high-end builds.

    Tributes of Harmony: Use these in the Undercity to earn guaranteed Rune drops (up to four per run).

    Uber Bosses: Great source of higher-grade and Legendary runes.

    Runecrafting: Use three runes to craft one of a random type. Be careful not to consume your important runes—stash them first.

    Tip: Legendary rune conversions always yield another Legendary. For rare and magic ones, there's an 85% chance of same-tier and 15% chance of an upgrade.

6. Ancestral Gear: The Gold Standard

Ancestral items are vastly superior to standard legendaries:

    Item Level 800 (vs. 750).

    Higher affix ranges and base stats.

    Greater Affixes (G-Affixes): These roll at 1.5x the power of standard affixes.

Items can roll up to four G-Affixes, making them incredibly rare and valuable (sometimes trading for billions of gold). However, even one perfect G-Affix that matches your build needs (e.g., max resource) can be a game-changer.

Best Ways to Farm Ancestrals:

    High-Tier Pit Runs: Excellent drop chances, glyph upgrades, and Obol farming.

    Undercity Legendary Tributes: Guaranteed ancestral legendaries.

    Obol Vendor: With seasonal blessings, you have a chance to roll high-tier loot.

7. Uber Bosses: The Mythical Path

Uber bosses like Duriel, Andariel, and Varshan are essential:

    Drop mythical gear, legendary runes, and high-value uniques.

    Group up to rotate boss summons and maximize fights per run.

    Mythicals dropped can be salvaged into Resplendent Sparks (required for crafting).

8. Crafting Mythical Uniques: The Endgame Goal

To craft a mythical unique, you need:

    2 Resplendent Sparks: Earned from:

        Completing the Seasonal Journey.

        Defeating your first Uber boss (although this is bugged for some players).

    6/6 runes in three categories.

    A visit to the Jeweler (not the Blacksmith) for crafting specific items.

    Tip: Avoid using Sparks to craft a random Mythical Unique cache. Save them for a targeted item your build needs (e.g., Tyrael's Might).

Even the Obol Vendor has a tiny chance of giving you a mythical—especially with the seasonal Urn of Curiosity active (adds 40% chance for a second item).

9. Trading and Community Help

If RNG isn't on your side, the Diablo 4 trading community can be a powerful ally. Trade unwanted mythicals, gear, or runes to complete your build. Max-level characters unlock bartering points, giving access to powerful vendor gear and keeping the loot flowing even when content is exhausted.

Final Thoughts: Reaching Pinnacle Power

Becoming OP in Diablo 4's endgame isn't just about playing more—it's about playing smart. Use the right farming methods, optimize your affixes cheap Diablo 4 Items, chase the best gear, and harness the power of runes and mythicals. With patience, knowledge, and persistence, you'll push pit tiers into the 80s and beyond, carving your legacy into the world of Sanctuary.

Stay strong, stay ruthless—and see you at the top of the leaderboard.